Recent insight into the pathogenicity mechanisms of the emergent pathogen Photorhabdus asymbiotica

Sonia C.P. Costa (1, 2) , Carolina Varela Chavez (1) , Grégory Jubelin (1) , Alain Givaudan (1) , Jean-Michel Escoubas (3) , Michel Brehélin (1, 4) , Robert Zumbihl (1, 5)

1 EMIP - Ecologie microbienne des insectes et interactions hôte-pathogène
2 Departamento de Biologia
3 DGIMI - Diversité, Génomes & Interactions Microorganismes - Insectes [Montpellier]
4 CNRS - Centre National de la Recherche Scientifique
5 UM2 - Université Montpellier 2 - Sciences et Techniques

Photorhabdus asymbiotica is unique among the entomopathogenic bacteria of this genus in also being able to infect humans, leading to its isolation from some clinical samples. Recent comparative genomics data and the results of studies of interactions between bacteria and cells provide insight into the adaptation of this bacterium to its new niche, the human body

Mots clés: PHOTORABDUS ASYMBIOTICA; EMERGENT PATHOGEN; INSECT; MAN; PHAGOCYTOSIS

Mots clés: COMPARATIVE GENOMICS; APOPTOSIS; VIRULENCE FACTORS; GENOMIQUE; RELATION HOTE-PARASITE

Domaines: Microbiologie et Parasitologie

Sonia C.P. Costa, Carolina Varela Chavez, Grégory Jubelin, Alain Givaudan, Jean-Michel Escoubas, et al.. Recent insight into the pathogenicity mechanisms of the emergent pathogen Photorhabdus asymbiotica. Microbes and Infection, 2010, 12 (3), pp.182-189. ⟨10.1016/j.micinf.2009.12.003⟩. ⟨hal-02663167⟩