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Journal Articles Cancer/Radiothérapie Year : 2020

Hodkgin lymphoma concomitant of tuberculosis, a therapeutic challenge for multidisciplinary management

Lymphome de Hodgkin concomitant d'une tuberculose, un challenge thérapeutique pour une prise en charge pluridisciplinaire

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Abstract

Hodgkin lymphoma (HL) is a disease characterized by a high curability rate, and the treatment benefit-risk balance must be carefully addressed to achieve complete disease control with low risk of long-term toxicities. Most patients are treated with a combination of chemotherapy and radiotherapy, after disease staging and response to treatment evaluated by FDG PET/CT. We report the case of a 28-year-old patient concomitantly diagnosed of a Hodgkin lymphoma and active tuberculosis. Initial staging was difficult due to pulmonary and abdominal tuberculosis localization that induced FDG PET/CT hypermetabolism. Anti-tuberculosis treatment was first started, allowing secondary an early accurate Hodgkin lymphoma staging by FDG PET/CT. The patient was then treated by chemotherapy and radiotherapy. Helical TomoTherapy® was used with involved site (IS) irradiation volume was performed to decrease the high doses to organs-at-risk (OAR), especially lungs in this context of tuberculosis.
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Dates and versions

hal-02927390 , version 1 (22-08-2022)

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Attribution - NonCommercial - CC BY 4.0

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Alice Boilève, Frédérique Kuhnowski, Thibaut Cassou-Mounat, Nina Jehanno, Youlia M. Kirova. Hodkgin lymphoma concomitant of tuberculosis, a therapeutic challenge for multidisciplinary management. Cancer/Radiothérapie, 2020, 24 (4), pp.335-339. ⟨10.1016/j.canrad.2020.02.005⟩. ⟨hal-02927390⟩
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