Interplay between primary familial brain calcification-associated SLC20A2 and XPR1 phosphate transporters requires inositol polyphosphates for control of cellular phosphate homeostasis

Uriel López-Sánchez (1) , Sandrine Tury (2, 3) , Gaël Nicolas (4) , Miranda Wilson (5) , Snejana Jurici , Xavier Ayrignac (6) , Valérie Courgnaud (1) , Adolfo Saiardi (7) , Marc Sitbon (1) , Jean-Luc Battini (1, 3)

1 IGMM - Institut de Génétique Moléculaire de Montpellier
2 Pharmacogenomics Unit [Paris]
3 IRIM - Institut de Recherche en Infectiologie de Montpellier
4 CRI (UMR_S_1149 / ERL_8252 / U1149) - Centre de recherche sur l'Inflammation
5 Department of Medical Genetics
6 CRC Sclérose en Plaques [Montpellier]
7 MRC-Cell Biology Unit

Domaines: Sciences du Vivant [q-bio]

Uriel López-Sánchez, Sandrine Tury, Gaël Nicolas, Miranda Wilson, Snejana Jurici, et al.. Interplay between primary familial brain calcification-associated SLC20A2 and XPR1 phosphate transporters requires inositol polyphosphates for control of cellular phosphate homeostasis. Journal of Biological Chemistry, 2020, 295 (28), pp.9366-9378. ⟨10.1074/jbc.RA119.011376⟩. ⟨hal-02989425⟩