Regulation of Kinesin-1 activity by Salmonella enterica effectors PipB2 and SifA

Lucrecia Alberdi , Alexandra Vergnes , Jean-Baptiste Manneville , Dumizulu L Tembo , Ziyan Fang , Yaya Zhao , Nina Schroeder , Audrey Dumont , Margaux Lagier , Patricia Bassereau (1) , Lorena Redondo-Morata , Jean- Pierre Gorvel , Stéphane Méresse

1 PCC - Laboratoire Physico-Chimie Curie [Institut Curie]

The Kinesin-1 motor protein plays a key role in controlling the membrane exchanges necessary for the intracellular survival of Salmonella, a pathogenic bacterium. This article highlights the complexity of Kinesin-1 regulation by Salmonella effector proteins.

Domaines: Matière Molle [cond-mat.soft]; Organisation et fonctions cellulaires [q-bio.SC]; Biophysique

Lucrecia Alberdi, Alexandra Vergnes, Jean-Baptiste Manneville, Dumizulu L Tembo, Ziyan Fang, et al.. Regulation of Kinesin-1 activity by Salmonella enterica effectors PipB2 and SifA. Journal of Cell Science, 2020, 133 (9), pp.jcs239863. ⟨10.1242/jcs.239863⟩. ⟨hal-03035354⟩