Self-organization of a virtual multicellular organism by adding a shape model in the Cellular Potts Model.

S. Tripodi , Pascal Ballet (1) , Vincent Rodin (1)

1 Lab-STICC_UBO_CID_IHSEV

The Cellular Potts Model (CPM) is a cellular automaton (CA) allowing to model the morphogenesis of living cells. It characterizes a cell by its volume, surface and type. The CPM has already been used to simulate several models of cell self-organization. However, the cell shape is under constraint i:e: it does not implies a unique shape. We propose a definition and an implementation of the cell shape in the CPM, that can target a unique shape. The results of our simulations show that this target shape can structure and maintain the cellular tissue since the beginning of its growth and during its life.

S. Tripodi, Pascal Ballet, Vincent Rodin. Self-organization of a virtual multicellular organism by adding a shape model in the Cellular Potts Model.. Twelfth International Conference on the Synthesis and Simulation of Living Systems - ALIFE XII ., Aug 2010, Odense-Denmark., Denmark. pp.249-256. ⟨hal-00662566⟩