Characterization of a Clone of Mycobacterium tuberculosis Clinical Isolates with Mutations in KatG (A110V), EthA (Q269STOP), and the inhA Promoter (−15C→T)

Florence Brossier; Christophe Sola; Christine Bernard; Vincent Jarlier; Nicolas Veziris; Wladimir Sougakoff

doi:10.1128/JCM.01537-15

Journal articles

Characterization of a Clone of Mycobacterium tuberculosis Clinical Isolates with Mutations in KatG (A110V), EthA (Q269STOP), and the inhA Promoter (−15C→T)

Florence Brossier ^{1, 2} Christophe Sola ³ Christine Bernard ^{1, 2} Vincent Jarlier ^{1, 2} Nicolas Veziris ^{1, 2} Wladimir Sougakoff ^{1, 2}

1 CNR-MyRMA - Centre National de Référence des Mycobactéries et de la Résistance aux Antituberculeux [CHU Pitié-Salpêtrière]

2 CIMI - Centre d'Immunologie et de Maladies Infectieuses

3 IGM - Institut de génétique et microbiologie [Orsay]

Abstract : Among the Mycobacterium tuberculosis clinical isolates collected during the 2003-2014 period at the French National Reference Center for Mycobacteria, 29 showed a remarkable combination of mutations in katG, ethA, and the inhA promoter. The aim of this study was to establish the epidemiologic and molecular features of these isolates.

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Journal articles

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Life Sciences [q-bio] / Microbiology and Parasitology

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https://hal.sorbonne-universite.fr/hal-01316512
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Submitted on : Tuesday, May 17, 2016 - 11:27:58 AM
Last modification on : Wednesday, June 15, 2022 - 3:48:18 AM

Characterization of a Clone of Mycobacterium tuberculosis Clinical Isolates with Mutations in KatG (A110V), EthA (Q269STOP), and the inhA Promoter (−15C→T)

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Characterization of a Clone of Mycobacterium tuberculosis Clinical Isolates with Mutations in KatG (A110V), EthA (Q269STOP), and the inhA Promoter (−15C→T)

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