Enhanced spatial resolution of MALDI images using silicon masks - Université Pierre et Marie Curie Accéder directement au contenu
Communication Dans Un Congrès Année : 2007

Enhanced spatial resolution of MALDI images using silicon masks

Résumé

This paper reports on simple, efficient and economical methods to increase MALDI image resolution. It is not currently possible to focus the diameter of a MALDI laser down to 50x50µm², i.e. 2500µm², without decreasing signal intensity. But using Silicon masks openings features, it might even be decreased to about 15x50µm², i.e. 750µm². Furthermore, the presence of a mask on the tissue section sample may result in a significant increase in the signal intensity for high m/z ratios. Finally, a huge advantage of the masks is their ease of adaptability on any MALDI mass spectrometer.
Fichier principal
Vignette du fichier
Verplanck2007.pdf (90.64 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-00284454 , version 1 (09-06-2022)

Licence

Paternité

Identifiants

  • HAL Id : hal-00284454 , version 1

Citer

Nicolas Verplanck, Maxence Wisztorski, Jonathan Stauber, J.C. Camart, Michel Salzet, et al.. Enhanced spatial resolution of MALDI images using silicon masks. 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2007, 2007, Paris, France. pp.41-43. ⟨hal-00284454⟩
44 Consultations
14 Téléchargements

Partager

Gmail Facebook X LinkedIn More