β,γ-Diamino acid: an original building block for hybrid α/γ-peptide synthesis with extra hydrogen bond donating group. - Archive ouverte HAL Access content directly
Journal Articles Amino Acids Year : 2014

β,γ-Diamino acid: an original building block for hybrid α/γ-peptide synthesis with extra hydrogen bond donating group.

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Abstract

: Using a β,γ-diamino acid, several small hybrid α/γ peptides have been synthesized and their conformations investigated through extensive NMR studies and molecular dynamics. A tripeptide and a tetrapeptide have thus shown several hydrogen bonds in solution, including a 13-membered ring involving the β-nitrogen.
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hal-01064605 , version 1 (16-09-2014)

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Andrii Stanovych, Régis Guillot, Cyrille Kouklovsky, Emeric Miclet, Valérie Alezra. β,γ-Diamino acid: an original building block for hybrid α/γ-peptide synthesis with extra hydrogen bond donating group.. Amino Acids, 2014, 46 (12), pp.2753-2757. ⟨10.1007/s00726-014-1831-y⟩. ⟨hal-01064605⟩
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