[A tamponade complicating an acute eosinophilic pericarditis due to a myeloproliferative/myelodysplastic syndrome.]

Une tamponnade compliquant une pericardite a eosinophiles au cours d'un syndrome myeloproliferatif/myelodysplasique.

Claire de Moreuil (1) , A Lieber (2) , Z Marjanovic (3) , A Bobbio (4) , Z Alavi (5) , J Blacher (2) , J-P Marie (3, 6)

1 DMIP - Brest - Département de Médecine Interne et Pneumologie [Brest]
2 Centre de diagnostic
3 CHU Saint-Antoine [AP-HP]
4 Service de chirurgie thoracique et vasculaire
5 CIC - Brest - Centre d'Investigation Clinique
6 Centre de recherche en myologie

Cardiac involvement in eosinophilia is potentially fatal and requires early diagnosis and prompt treatment. We report here the case of a 71-year-old female patient with eosinophilia>10,000/mm3 for 2 months due to a myeloproliferative/myelodysplastic syndrome, with a rapidly progressive exertional dyspnea explained by an important circumferential eosinophilic pericarditis. Due to a rapid evolution to a tamponade, an emergent surgical drainage was performed. Subsequent medical treatment combined high-dose corticosteroids (1mg/kg/day) with hydroxyurea and imatinib. The outcome was favourable with regression of the effusion, of the volume overload symptoms and decrease in eosinophilia.

Mots clés: Tamponnade; Péricardite; Hyperéosinophilie; Syndrome myéloprolifératif/myélodysplasique; Imatinib

Domaines: Sciences du Vivant [q-bio]

Claire de Moreuil, A Lieber, Z Marjanovic, A Bobbio, Z Alavi, et al.. [A tamponade complicating an acute eosinophilic pericarditis due to a myeloproliferative/myelodysplastic syndrome.]. Annales de Cardiologie et d'Angéiologie, 2015, 65 (1), pp.51-53. ⟨10.1016/j.ancard.2014.12.002⟩. ⟨hal-01259801⟩