Pre-eclampsia: a Life-threatening Pregnancy Syndrom

Andrea Brazdova (1, 2) , Alena Keprova (3) , Jarmila Zidkova (1) , Jindrich Madar (4)

1 ICT - Institute of Chemical Technology [Prague]
2 CRC - Centre de Recherche des Cordeliers
3 CAS - Czech Academy of Sciences [Prague]
4 Institute for the Care of Mother and Child

Pre-eclampsia is a serious pathological state affecting 5-10% of pregnant women. Currently, it is diagnosed in the second half of pregnancy, particularly after the 20th week. Symptoms mostly correspond to the changes of blood vessels and kidneys. The severity of pre-eclampsia is proportional to symptomatic manifestations, thus the more symptoms present, the higher is of pre-eclampsia development. Although there are several studies dealing with pre-eclampsia pathology, the complete etiology is still unknown. In this review paper, several theories are presented and discussed.

Mots clés: pregnancy; oxidative stress; placenta; pre-eclampsia

Domaines: Chimie; Médecine humaine et pathologie

Andrea Brazdova, Alena Keprova, Jarmila Zidkova, Jindrich Madar. Pre-eclampsia: a Life-threatening Pregnancy Syndrom. Brazilian Archives of Biology and Technology, 2014, 57 (5), pp.701-705. ⟨10.1590/S1516-8913201402449⟩. ⟨hal-01311328⟩