Myelin and cortical bone short-T2 quantification using saturation and diffusion-based long-T2 suppression in a steady-state 3D-UTE sequence

Lucas Soustelle (1) , Paulo Loureiro de Sousa (1) , Julien Lamy (1) , Mathieu Santin (2) , François Rousseau (3, 4) , Jean-Paul Armspach (1)

1 ICube - Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie
2 ICM - Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute
3 ITI - Département Image et Traitement Information
4 LaTIM - Laboratoire de Traitement de l'Information Medicale

Imaging of the very-short T2 tissues in the head is challenging in that the signals decay very rapidly (T2 < 1 ms), as well as their signal quantity being often overwhelmed by long-T2 relaxing components (fat, free-water). In this work, we explore the feasibility of short-T2 quantification in the white matter and in the cortical bone using a novel method for long-T2 suppression based on diffusion and coherence effects in a steady-state 3D-UTE sequence.

Domaines: Traitement du signal et de l'image [eess.SP]; Imagerie

Lucas Soustelle, Paulo Loureiro de Sousa, Julien Lamy, Mathieu Santin, François Rousseau, et al.. Myelin and cortical bone short-T2 quantification using saturation and diffusion-based long-T2 suppression in a steady-state 3D-UTE sequence. ISMRM'17 : 25th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine, Apr 2017, Honolulu, United States. ⟨hal-01802707⟩