Synthesis of 6-Hydroxyaurone Analogues and Evaluation of Their α-Glucosidase Inhibitory and Glucose Consumption-Promoting Activity: Development of Highly Active 5,6-Disubstituted Derivatives

Hua Sun (1) , Weina Ding (1) , Xiaotong Song (1) , Dong Wang (1) , Mingzhu Chen (1) , Kaili Wang (1) , Yazhou Zhang (1) , Peng Yuan (1) , Ying Ma (1) , Runling Wang (1) , Robert H. Dodd (1, 2) , Yongmin Zhang (3) , Kui Lu (1) , Peng Yu (1)

1 TUST - Tianjin University of Science and Technology
2 ICSN - Institut de Chimie des Substances Naturelles
3 GOBS - Glycochimie Organique Biologique et Supramoléculaire

Keywords: GOBS; POLE 3

Domains: Chemical Sciences

Hua Sun, Weina Ding, Xiaotong Song, Dong Wang, Mingzhu Chen, et al.. Synthesis of 6-Hydroxyaurone Analogues and Evaluation of Their α-Glucosidase Inhibitory and Glucose Consumption-Promoting Activity: Development of Highly Active 5,6-Disubstituted Derivatives. Bioorganic and Medicinal Chemistry Letters, 2017, 27 (15), pp.3226--3230. ⟨10.1016/j.bmcl.2017.06.040⟩. ⟨hal-02891079⟩