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Article Dans Une Revue Biophysical Journal Année : 1999

A New Determination of the Shear Modulus of the Human Erythrocyte Membrane Using Optical Tweezers

Résumé

Optical tweezers are used to apply calibrated forces to human erythrocytes, via small silica beads bound to their membrane. The shear modulus μ of the membrane is inferred from measurements of the cell deformation in the small strain linear regime. We find the same result μ = 2.5 ± 0.4 μN/m for both discotic and nearly spherical swollen cells. This value is smaller than the one deduced from micropipettes experiments. However the two methods do not operate in the same deformation regime and are not expected to lead to the same result.

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hal-03876191 , version 1 (28-11-2022)

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Sylvie Hénon, Guillaume Lenormand, Alain Richert, François Gallet. A New Determination of the Shear Modulus of the Human Erythrocyte Membrane Using Optical Tweezers. Biophysical Journal, 1999, 76 (2), pp.1145-1151. ⟨10.1016/S0006-3495(99)77279-6⟩. ⟨hal-03876191⟩
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