Diaphragmatic Function Is Preserved during Severe Hemorrhagic Shock in the Rat

Serge Carreira (1) , Matthieu Le Dinh (2) , Marc Soubeyrand (3) , Marie-Pierre Poloujadoff , Bruno Riou (4) , Thomas Similowski (5) , Catherine Coirault (6) , Alexandre Demoule (5)

1 ICAN - Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases
2 SU - Sorbonne Université
3 AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP)
4 UPMC - Université Pierre et Marie Curie - Paris 6 - UFR de Médecine Pierre et Marie Curie
5 CHU Pitié-Salpêtrière [AP-HP]
6 Centre de recherche en myologie

Background: Acute diaphragmatic dysfunction has been reported in septic and cardiogenic shock, but few data are available concerning the effect of hemorrhagic shock on dia-phragmatic function. The authors examined the impact of a hemorrhagic shock on the diaphragm. Methods: Four parallel groups of adult rats were submitted to hemorrhagic shock induced by controlled exsanguination

Domaines: Sciences du Vivant [q-bio]

Serge Carreira, Matthieu Le Dinh, Marc Soubeyrand, Marie-Pierre Poloujadoff, Bruno Riou, et al.. Diaphragmatic Function Is Preserved during Severe Hemorrhagic Shock in the Rat. Anesthesiology, 2014, 120 (2), pp.425-435. ⟨10.1097/ALN.0000000000000011⟩. ⟨inserm-02426553⟩