%0 Journal Article
%T Analysis of distribution in the human, pig, and rat genomes points toward a general subtelomeric origin of minisatellite structures.
%+ SYNAPSE
%+ Centre de Recherche des Cordeliers (CRC (UMR_S 872))
%+ The Wellcome Trust Centre for Human Genetics [Oxford]
%+ Laboratoire de Génétique Cellulaire (LGC)
%+ Unité de recherche Pharmacologie-Toxicologie (UPT)
%+ McGill University and Genome Quebec Innovation Centre
%+ Institut de biologie et chimie des protéines [Lyon] (IBCP)
%+ Institut de génétique humaine (IGH)
%+ Institut de génétique et microbiologie [Orsay] (IGM)
%+ École Nationale Supérieure de Techniques Avancées (ENSTA Paris)
%A Amarger, V
%A Gauguier, D
%A Yerle, Martine, M.
%A Apiou, F
%A Pinton, P
%A Giraudeau, F
%A Monfouilloux, S
%A Lathrop, M
%A Dutrillaux, B
%A Buard, J
%A Vergnaud, Gilles
%< avec comité de lecture
%@ 0888-7543
%J Genomics
%I Elsevier
%V 52
%N 1
%P 62-71
%8 1998-08-15
%D 1998
%R 10.1006/geno.1998.5365
%M 9740672
%Z Life Sciences [q-bio]
%Z Life Sciences [q-bio]/GeneticsJournal articles
%X We have developed approaches for the cloning of minisatellites from total genomic libraries and applied these approaches to the human, rat, and pig genomes. The chromosomal distribution of minisatellites in the three genomes is strikingly different, with clustering at chromosome ends in human, a seemingly almost even distribution in rat, and an intermediate situation in pig. A closer analysis, however, reveals that interstitial sites in pig and rat often correspond to terminal cytogenetic bands in human. This observation suggests that minisatellites are created toward chromosome ends and their internalization represents secondary events resulting from rearrangements involving chromosome ends.
%G English
%2 https://hal-ensta-paris.archives-ouvertes.fr/hal-01160637/document
%2 https://hal-ensta-paris.archives-ouvertes.fr/hal-01160637/file/Genomics.1998_1.pdf
%L hal-01160637
%U https://hal-ensta-paris.archives-ouvertes.fr/hal-01160637
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