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Journal articles
Genetic mapping of three human homologues of murine t-complex genes localizes TCP10 to 6q27, 15 cM distal to TCP1 and PLG.
H Blanché
1
L G Wright
Gilles Vergnaud
2, 3
B de Gouyon
V Lauthier
L M Silver
J Dausset
4
H M Cann
R S Spielman
H Blanché 1
Author
L G Wright
Author
Gilles Vergnaud 2, 3
Mail :
Author IdHAL : gilles-vergnaud ResearcherId : http://www.researcherid.com/rid/P-1304-2015 ORCID : https://orcid.org/0000-0003-0913-194X
B de Gouyon
Author
R S Spielman
Author
1
CEPH - Centre d'Etude du Polymorphisme Humain (27, rue Juliette Dodu, 75010 Paris - France)
- UPD7 - Université Paris Diderot - Paris 7 (5 rue Thomas-Mann - 75205 Paris cedex 13 - France)
- IUH - Institut Universitaire d'Hématologie (Université Paris Diderot, 1 Av. Claude Vellefaux 75010 Paris - France)
- UPD7 - Université Paris Diderot - Paris 7 (5 rue Thomas-Mann - 75205 Paris cedex 13 - France)
- Fondation Jean Dausset (France)
2
IGM - Institut de génétique et microbiologie [Orsay] (Bâtiments 400 et 409
UFR des Sciences - Université Paris-Sud 11
15, rue Georges Clémenceau - F 91405 ORSAY Cedex - France)
- CNRS - Centre National de la Recherche Scientifique : UMR8621 (France)
- UP11 - Université Paris-Sud - Paris 11 (Bâtiment 300 - 91405 Orsay cedex - France)
3
ENSTA Paris - École Nationale Supérieure de Techniques Avancées (828, boulevard des Maréchaux 91762 Palaiseau Cedex - France)
4
SRHI - UMR_E 05 - Service de Recherche en Hémato-Immunologie (Université Paris Diderot Institut Universitaire d'Hématologie (IUH) Hôpital Saint Louis 1 avenue Claude Vellefaux 75010 Paris - France)
- UPD7 - Université Paris Diderot - Paris 7 : UMR_E 05 (5 rue Thomas-Mann - 75205 Paris cedex 13 - France)
- CEA - Commissariat à l'énergie atomique et aux énergies alternatives : DRF/JACOB (Centre de Saclay Centre de Grenoble Centre de Cadarache etc - France)
Abstract : Human homologues of mouse t-complex genes have been cloned and localized physically to chromosome 6p or 6q. TCP1, TCP10, and PLG are human homologues of genes located in the proximal portion of the t-complex on mouse chromosome 17. We present here results of genetic mapping of these human t-complex homologues previously localized to 6q25-q27, 6q21-q27, and 6q26-q27, respectively, by physical techniques. TCP1 and PLG do not recombine with each other and are separated from TCP10 by about 15 cM, while the corresponding mouse genes are no more than 4 cM apart. Genetic mapping with markers well localized cytogenetically places TCP1 and PLG proximal to TCP10 and localizes the latter to the cytogenetic band 6q27. It is likely that the organization of human t-complex homologues on 6q is similar to that of t haplotypes rather than that of wildtype murine chromosome 17.
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Journal articles
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https://hal-ensta-paris.archives-ouvertes.fr//hal-01160689
Contributor : Gilles Vergnaud <>
Submitted on : Saturday, June 6, 2015 - 5:25:44 PM
Last modification on : Sunday, May 31, 2020 - 11:50:03 AM
Contributor : Gilles Vergnaud <>
Submitted on : Saturday, June 6, 2015 - 5:25:44 PM
Last modification on : Sunday, May 31, 2020 - 11:50:03 AM
Identifiers
- HAL Id : hal-01160689, version 1
- PUBMED : 1572657
Citation
H Blanché, L G Wright, Gilles Vergnaud, B de Gouyon, V Lauthier, et al.. Genetic mapping of three human homologues of murine t-complex genes localizes TCP10 to 6q27, 15 cM distal to TCP1 and PLG.. Genomics, Elsevier, 1992, 12 (4), pp.826-8. ⟨hal-01160689⟩
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