A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes.

F Rouyer M C Simmler 1 C Johnsson Gilles Vergnaud 2, 3 H J Cooke J Weissenbach 4
1 IJM - Institut Jacques Monod
2 IGM - Institut de génétique et microbiologie [Orsay]
3 ENSTA Paris - École Nationale Supérieure de Techniques Avancées
4 GENOSCOPE - Genoscope - Centre national de séquençage [Evry]
Abstract : Three independent pseudoautosomal loci are linked to sex determination at frequencies which define a gradient of linkage. The segregation patterns of these loci indicate that X/Y recombination results from a single obligatory meiotic crossing-over in the pseudoautosomal region. Recombination in male germ cells in the terminal regions of the short arms of the X and Y chromosomes in 10-fold greater than between the same regions of the X chromosomes in female germ cells.
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Journal articles
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https://hal-ensta-paris.archives-ouvertes.fr//hal-01160710
Contributor : Gilles Vergnaud <>
Submitted on : Saturday, June 6, 2015 - 5:53:41 PM
Last modification on : Thursday, October 10, 2019 - 11:36:02 AM

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  • HAL Id : hal-01160710, version 1
  • PUBMED : 3941746

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ENSTA | UNIV-PARIS7 | IJM | CEA | I2BC | USPC | JACOB | CEA-DRF | GENOSCOPE

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F Rouyer, M C Simmler, C Johnsson, Gilles Vergnaud, H J Cooke, et al.. A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes.. Nature, Nature Publishing Group, 1996, 319 (6051), pp.291-5. ⟨hal-01160710⟩

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