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Journal articles
A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes.
F Rouyer
Author
M C Simmler 1
Author
C Johnsson
Author
Gilles Vergnaud 2, 3
Mail :
Author IdHAL : gilles-vergnaud ResearcherId : http://www.researcherid.com/rid/P-1304-2015 ORCID : https://orcid.org/0000-0003-0913-194X
H J Cooke
Author
J Weissenbach 4
Author
1
IJM (UMR_7592) - Institut Jacques Monod (Université Paris Diderot, Bât. Buffon, 15 rue Hélène Brion, 75205 Paris cédex 13 - France)
- UPD7 - Université Paris Diderot - Paris 7 : UMR_7592 (5 rue Thomas-Mann - 75205 Paris cedex 13 - France)
- CNRS - Centre National de la Recherche Scientifique : UMR_7592 (France)
2
IGM - Institut de génétique et microbiologie [Orsay] (Bâtiments 400 et 409
UFR des Sciences - Université Paris-Sud 11
15, rue Georges Clémenceau - F 91405 ORSAY Cedex - France)
- CNRS - Centre National de la Recherche Scientifique : UMR8621 (France)
- UP11 - Université Paris-Sud - Paris 11 (Bâtiment 300 - 91405 Orsay cedex - France)
3
ENSTA Paris - École Nationale Supérieure de Techniques Avancées (828, boulevard des Maréchaux 91762 Palaiseau Cedex - France)
4
GENOSCOPE - Genoscope - Centre national de séquençage [Evry] (2, rue Gaston Crémieux CP5706 91057 EVRY Cedex - France)
- Université Paris-Saclay (Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin - France)
- DRF (CEA) - Direction de Recherche Fondamentale (CEA) : DRF/JACOB (Direction de Recherche Fondamentale
Fundamental Research Division
CEA Saclay
91191 Gif-sur-Yvette
- France)
- CEA - Commissariat à l'énergie atomique et aux énergies alternatives (Centre de Saclay Centre de Grenoble Centre de Cadarache etc - France)
Abstract : Three independent pseudoautosomal loci are linked to sex determination at frequencies which define a gradient of linkage. The segregation patterns of these loci indicate that X/Y recombination results from a single obligatory meiotic crossing-over in the pseudoautosomal region. Recombination in male germ cells in the terminal regions of the short arms of the X and Y chromosomes in 10-fold greater than between the same regions of the X chromosomes in female germ cells.
Document type :
Journal articles
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Complete list of metadatas
https://hal-ensta-paris.archives-ouvertes.fr//hal-01160710
Contributor : Gilles Vergnaud <>
Submitted on : Saturday, June 6, 2015 - 5:53:41 PM
Last modification on : Wednesday, June 17, 2020 - 3:42:03 PM
Contributor : Gilles Vergnaud <>
Submitted on : Saturday, June 6, 2015 - 5:53:41 PM
Last modification on : Wednesday, June 17, 2020 - 3:42:03 PM
Identifiers
- HAL Id : hal-01160710, version 1
- PUBMED : 3941746
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Citation
F Rouyer, M C Simmler, C Johnsson, Gilles Vergnaud, H J Cooke, et al.. A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes.. Nature, Nature Publishing Group, 1996, 319 (6051), pp.291-5. ⟨hal-01160710⟩
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