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A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes.

Abstract : Three independent pseudoautosomal loci are linked to sex determination at frequencies which define a gradient of linkage. The segregation patterns of these loci indicate that X/Y recombination results from a single obligatory meiotic crossing-over in the pseudoautosomal region. Recombination in male germ cells in the terminal regions of the short arms of the X and Y chromosomes in 10-fold greater than between the same regions of the X chromosomes in female germ cells.
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Submitted on : Saturday, June 6, 2015 - 5:53:41 PM
Last modification on : Sunday, June 26, 2022 - 2:18:48 AM

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François Rouyer, Marie-Christine Simmler, Christophe Johnsson, Gilles Vergnaud, Howard J. Cooke, et al.. A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes.. Nature, Nature Publishing Group, 1986, 319 (6051), pp.291-5. ⟨10.1038/319291a0⟩. ⟨hal-01160710⟩

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