Quantification of Parkinsonian Kinematic Patterns in Body-Segment Regions During Locomotion
Résumé
Diagnosis and treatment of Parkinson's Disease (PD) are typically supported by a kinematic gait analysis. Nonetheless, the main drawbacks of the classical analysis, based on a reduced set of markers, are the loss of small dynamical changes, the invasive methodology, and the sparse representation from few points, restricting the disease analysis. This work aims to perform a robust regional kinematic characterization, which may result in a potential digital biomarker of the disease to complement personalized analysis, treatment and monitoring of PD. Methods: This work introduces a markerless computational framework based on a full body-segment kinematic characterization related with PD motor alterations. Firstly, a set of dense motion trajectories are computed to represent locomotion. Such trajectories are grouped using a deep learning based body segmentation, that partitions the human silhouette into regions corresponding to the head, trunk and limbs. Each resultant region is described using dartboard-like kinematic histograms computed along the trajectories.
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